HPr, General component of the sugar [SW|phosphotransferase system] (PTS)

HPr, General component of the sugar phosphotransferase system (PTS)

Protein HPr N(pi)-phospho-L-histidine + protein EIIA = protein HPr + protein EIIA N(tau)-phospho-L-histidine (according to Swiss-Prot)

Protein HPr N(pi)-phospho-L-histidine protein EIIA = protein HPr protein EIIA N(tau)-phospho-L-histidine (according to Swiss-Prot) Protein HPr N(pi)-phospho-L-histidine protein EIIA = protein [[protein|PtsH|HPr]]]] protein EIIA N(tau)-phospho-L-histidine

transient phosphorylation by [[protein|PtsI|Enzyme I]] of the PTS on His-15

regulatory phosphorylation on Ser-46 by [[protein|HprK]] [Pubmed|2507315]

an extensive study on ''in vivo'' HPr phosphorylation can be found in Singh et al. (2008) [PubMed|18757537]

weak phosphorylation on Ser-12 [Pubmed|17218307]

''in vitro'' phosphorylated by [[protein|PrkC]] on Ser-12 [Pubmed|20389117]

transient phosphorylation by [[protein|PtsI|Enzyme I]]]] of the PTS on His-15

regulatory phosphorylation on Ser-46 by [[protein|HprK]] [Pubmed|2507315]

an extensive study on ''in vivo'' HPr phosphorylation can be found in Singh et al. (2008) [PubMed|18757537]

weak phosphorylation on Ser-12 [Pubmed|17218307]

''in vitro'' phosphorylated by [[protein|PrkC]] on Ser-12 [Pubmed|20389117]

[PDB|2HID] (NMR) [Pubmed|9336834]

[PDB|1KKM] (complex of ''L. casei'' [[protein|HprK]] with ''B. subtilis'' HPr-Ser-P)

[PDB|1KKL] (complex of ''Lactobacillus casei'' [[protein|HprK]] with ''B. subtilis'' HPr)

[PDB|3OQM] (complex of ''B. subtilis'' [[protein|CcpA]] with P-Ser-[[protein|PtsH|HPr]] and the [[gene|ackA]] operator site)

[PDB|3OQN] (complex of ''B. subtilis'' [[protein|CcpA]] with P-Ser-[[protein|PtsH|HPr]] and the [[gene|gntR]] operator site)

[PDB|3OQO] (complex of ''B. subtilis'' [[protein|CcpA]] with P-Ser-[[protein|PtsH|HPr]] and a optimal synthetic operator site)

[PDB|2HID] (NMR) [Pubmed|9336834]

[PDB|1KKM] (complex of ''L. casei'' [[protein|HprK]] with ''B. subtilis'' HPr-Ser-P)

[PDB|1KKL] (complex of ''Lactobacillus casei'' [[protein|HprK]] with ''B. subtilis'' HPr)

[PDB|3OQM] (complex of ''B. subtilis'' CcpA with P-Ser-[[protein|PtsH|HPr]] and the [[gene|ackA]] operator site)

[PDB|3OQN] (complex of ''B. subtilis'' CcpA with P-Ser-[[protein|PtsH|HPr]] and the [[gene|gntR]] operator site)

[PDB|3OQO] (complex of ''B. subtilis'' CcpA with P-Ser-[[protein|PtsH|HPr]] and a optimal synthetic operator site)

available in [SW|Jörg Stülke]'s lab:

MZ303 (cat)

GP507 ptsH1 (S46A)

GP506 (ptsH-H15A)

GP778 (Δ[[gene|glcT]]-[[gene|ptsG]]-[[gene|ptsH]]-[[gene|ptsI]]::spc) [Pubmed|22722928]

available in [SW|Jörg Stülke]'s lab:

MZ303 (cat)

GP507 ptsH1 (S46A)

GP506 (ptsH-H15A)

GP778 (replacement of [[gene|glcT]] and the [[gene|ptsG]]-[[gene|ptsH]]-[[gene|ptsI]] operon by a spc cassette), [Pubmed|22722928]